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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50438052'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50438052
PNG
(CHEMBL2409588)
Show SMILES COc1ccc(Nc2ncnc(Nc3ccccc3NC(C)=O)n2)c(OC)c1
Show InChI InChI=1S/C19H20N6O3/c1-12(26)22-14-6-4-5-7-15(14)23-18-20-11-21-19(25-18)24-16-9-8-13(27-2)10-17(16)28-3/h4-11H,1-3H3,(H,22,26)(H2,20,21,23,24,25)
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.11E+4n/an/an/an/an/an/a



Universit£ Paris Descartes

Curated by ChEMBL


Assay Description
Inhibition of pre-activated recombinant full length FAK (unknown origin) using ULight labeled poly(Glu/Tyr) as substrate after 1.6 hrs by TR-FRET ass...

Bioorg Med Chem Lett 23: 4552-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.038
BindingDB Entry DOI: 10.7270/Q2GM88RC
More data for this
Ligand-Target Pair