Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50306384![]() (5-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)... | J Med Chem 59: 4849-58 (2016) Article DOI: 10.1021/acs.jmedchem.6b00202 BindingDB Entry DOI: 10.7270/Q24T6M9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50306384![]() (5-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 87.1 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at human FFA1 receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescence spectrophotometry | J Med Chem 54: 6691-703 (2011) Article DOI: 10.1021/jm2005699 BindingDB Entry DOI: 10.7270/Q25T3MRW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50306384![]() (5-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA | Bioorg Med Chem Lett 20: 1298-301 (2010) Article DOI: 10.1016/j.bmcl.2009.10.052 BindingDB Entry DOI: 10.7270/Q2QC03KS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50306384![]() (5-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins... | J Med Chem 59: 4849-58 (2016) Article DOI: 10.1021/acs.jmedchem.6b00202 BindingDB Entry DOI: 10.7270/Q24T6M9W | |||||||||||
More data for this Ligand-Target Pair |