Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50563853 (CHEMBL4783033) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00892 BindingDB Entry DOI: 10.7270/Q2GH9NPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50563853 (CHEMBL4783033) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00892 BindingDB Entry DOI: 10.7270/Q2GH9NPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Mus musculus) | BDBM50563853 (CHEMBL4783033) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00892 BindingDB Entry DOI: 10.7270/Q2GH9NPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50563853 (CHEMBL4783033) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00892 BindingDB Entry DOI: 10.7270/Q2GH9NPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50563853 (CHEMBL4783033) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00892 BindingDB Entry DOI: 10.7270/Q2GH9NPC | |||||||||||
More data for this Ligand-Target Pair |