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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fusion glycoprotein F0' and Ligand = 'BDBM50542615'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fusion glycoprotein F0


(Human respiratory syncytial virus)		BDBM50542615
PNG
(CHEMBL4640277)
Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2ncccc12
Show InChI InChI=1S/C21H23N5O2/c27-11-2-1-10-24-16(12-17-18(24)4-3-8-23-17)14-25-20-13-22-9-7-19(20)26(21(25)28)15-5-6-15/h3-4,7-9,12-13,15,27H,1-2,5-6,10-11,14H2
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 158n/an/an/an/a



Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL


Assay Description
Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...

J Med Chem 63: 8046-8058 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00226
BindingDB Entry DOI: 10.7270/Q27H1P5V
More data for this
Ligand-Target Pair