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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fusion glycoprotein F0' and Ligand = 'BDBM50542641'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fusion glycoprotein F0


(Human respiratory syncytial virus)		BDBM50542641
PNG
(CHEMBL4641423)
Show SMILES Clc1ccc2n(CCCC#N)c(Cn3c4cnccc4n(C4CC4)c3=O)nc2n1
Show InChI InChI=1S/C20H18ClN7O/c21-17-6-5-15-19(24-17)25-18(26(15)10-2-1-8-22)12-27-16-11-23-9-7-14(16)28(20(27)29)13-3-4-13/h5-7,9,11,13H,1-4,10,12H2
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 10n/an/an/an/a



Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL


Assay Description
Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...

J Med Chem 63: 8046-8058 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00226
BindingDB Entry DOI: 10.7270/Q27H1P5V
More data for this
Ligand-Target Pair