Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human)) | BDBM50532017 (CHEMBL4529580) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 241 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Activation of human GIRK1/2 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay | Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027 BindingDB Entry DOI: 10.7270/Q2BV7M47 | |||||||||||
More data for this Ligand-Target Pair |