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Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50497373'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))
BDBM50497373
PNG
(CHEMBL3339115)
Show SMILES CC1(CC1)c1cc(NC(=O)Nc2cccc(F)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C20H19FN4O/c1-20(10-11-20)17-13-18(25(24-17)16-8-3-2-4-9-16)23-19(26)22-15-7-5-6-14(21)12-15/h2-9,12-13H,10-11H2,1H3,(H2,22,23,26)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 640n/an/an/an/an/an/a



Northwest A&F University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assay


Bioorg Med Chem Lett 24: 5102-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.061
BindingDB Entry DOI: 10.7270/Q2WD43JR
More data for this
Ligand-Target Pair