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Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50497401'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))
BDBM50497401
PNG
(CHEMBL3339108)
Show SMILES FC(F)(F)C1(CC1)c1cc(NC(=O)Nc2cc(Cl)cc(Cl)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C20H15Cl2F3N4O/c21-12-8-13(22)10-14(9-12)26-18(30)27-17-11-16(19(6-7-19)20(23,24)25)28-29(17)15-4-2-1-3-5-15/h1-5,8-11H,6-7H2,(H2,26,27,30)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Northwest A&F University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assay


Bioorg Med Chem Lett 24: 5102-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.061
BindingDB Entry DOI: 10.7270/Q2WD43JR
More data for this
Ligand-Target Pair