Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 4' and Ligand = 'BDBM50260335'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 4 (Homo sapiens (Human))	BDBM50260335 (CHEMBL4060989) Show SMILES CC(C)N1CCN(C\C=C\c2ccc(Cn3c(C)nc4c(C)cc(C)nc34)cc2)CC1 Show InChI InChI=1S/C26H35N5/c1-19(2)30-15-13-29(14-16-30)12-6-7-23-8-10-24(11-9-23)18-31-22(5)28-25-20(3)17-21(4)27-26(25)31/h6-11,17,19H,12-16,18H2,1-5H3/b7-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human GPR4 expressed in African green monkey COS7 cells assessed as inhibition of pH 6.5-induced cAMP accumulation after 30 mi...				Bioorg Med Chem 25: 4512-4525 (2017) Article DOI: 10.1016/j.bmc.2017.06.050 BindingDB Entry DOI: 10.7270/Q2NS0XB3
					More data for this Ligand-Target Pair
G-protein coupled receptor 4 (Rattus norvegicus)	BDBM50260335 (CHEMBL4060989) Show SMILES CC(C)N1CCN(C\C=C\c2ccc(Cn3c(C)nc4c(C)cc(C)nc34)cc2)CC1 Show InChI InChI=1S/C26H35N5/c1-19(2)30-15-13-29(14-16-30)12-6-7-23-8-10-24(11-9-23)18-31-22(5)28-25-20(3)17-21(4)27-26(25)31/h6-11,17,19H,12-16,18H2,1-5H3/b7-6+	UniProtKB/SwissProt GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at rat GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cA...				Bioorg Med Chem 25: 4512-4525 (2017) Article DOI: 10.1016/j.bmc.2017.06.050 BindingDB Entry DOI: 10.7270/Q2NS0XB3
					More data for this Ligand-Target Pair
G-protein coupled receptor 4 (Mus musculus)	BDBM50260335 (CHEMBL4060989) Show SMILES CC(C)N1CCN(C\C=C\c2ccc(Cn3c(C)nc4c(C)cc(C)nc34)cc2)CC1 Show InChI InChI=1S/C26H35N5/c1-19(2)30-15-13-29(14-16-30)12-6-7-23-8-10-24(11-9-23)18-31-22(5)28-25-20(3)17-21(4)27-26(25)31/h6-11,17,19H,12-16,18H2,1-5H3/b7-6+	UniProtKB/SwissProt GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at mouse GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by ...				Bioorg Med Chem 25: 4512-4525 (2017) Article DOI: 10.1016/j.bmc.2017.06.050 BindingDB Entry DOI: 10.7270/Q2NS0XB3
					More data for this Ligand-Target Pair