Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 6' and Ligand = 'BDBM191024'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM191024 (US10077266, Example 136 | US9181249, 136 | US97083...) Show SMILES CC(C)Nc1nc2CN(CCc2nc1N1CCN(Cc2ccc(F)cc2F)CC1)S(C)(=O)=O Show InChI InChI=1S/C22H30F2N6O2S/c1-15(2)25-21-22(27-19-6-7-30(33(3,31)32)14-20(19)26-21)29-10-8-28(9-11-29)13-16-4-5-17(23)12-18(16)24/h4-5,12,15H,6-11,13-14H2,1-3H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0279	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9181249 (2015) BindingDB Entry DOI: 10.7270/Q2HM577D
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM191024 (US10077266, Example 136 | US9181249, 136 | US97083...) Show SMILES CC(C)Nc1nc2CN(CCc2nc1N1CCN(Cc2ccc(F)cc2F)CC1)S(C)(=O)=O Show InChI InChI=1S/C22H30F2N6O2S/c1-15(2)25-21-22(27-19-6-7-30(33(3,31)32)14-20(19)26-21)29-10-8-28(9-11-29)13-16-4-5-17(23)12-18(16)24/h4-5,12,15H,6-11,13-14H2,1-3H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9708313 (2017) BindingDB Entry DOI: 10.7270/Q2ZP4858
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM191024 (US10077266, Example 136 | US9181249, 136 | US97083...) Show SMILES CC(C)Nc1nc2CN(CCc2nc1N1CCN(Cc2ccc(F)cc2F)CC1)S(C)(=O)=O Show InChI InChI=1S/C22H30F2N6O2S/c1-15(2)25-21-22(27-19-6-7-30(33(3,31)32)14-20(19)26-21)29-10-8-28(9-11-29)13-16-4-5-17(23)12-18(16)24/h4-5,12,15H,6-11,13-14H2,1-3H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US10077266 (2018) BindingDB Entry DOI: 10.7270/Q2T155PB
					More data for this Ligand-Target Pair