Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'GABA-A receptor; alpha-5/beta-3/gamma-2' and Ligand = 'BDBM50332374'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50332374 (9-Amino-2-cyclobutyl-5-(pyrimidin-2-yl)-2,3-dihydr...) Show SMILES Nc1c2c(cn(C3CCC3)c2=O)[nH]c2c(cccc12)-c1ncccn1 Show InChI InChI=1S/C19H17N5O/c20-16-12-6-2-7-13(18-21-8-3-9-22-18)17(12)23-14-10-24(11-4-1-5-11)19(25)15(14)16/h2-3,6-11,23H,1,4-5,20H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human alpha5beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 8374-82 (2010) Article DOI: 10.1016/j.bmc.2010.09.058 BindingDB Entry DOI: 10.7270/Q2FB536X
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50332374 (9-Amino-2-cyclobutyl-5-(pyrimidin-2-yl)-2,3-dihydr...) Show SMILES Nc1c2c(cn(C3CCC3)c2=O)[nH]c2c(cccc12)-c1ncccn1 Show InChI InChI=1S/C19H17N5O/c20-16-12-6-2-7-13(18-21-8-3-9-22-18)17(12)23-14-10-24(11-4-1-5-11)19(25)15(14)16/h2-3,6-11,23H,1,4-5,20H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	206	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to human alpha5beta3gamma2 GABA receptor expressed in Xenopus laevis oocytes				Bioorg Med Chem 18: 8374-82 (2010) Article DOI: 10.1016/j.bmc.2010.09.058 BindingDB Entry DOI: 10.7270/Q2FB536X
					More data for this Ligand-Target Pair