BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'GTPase KRas [G12D,Q61H]' and Ligand = 'BDBM485666'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
GTPase KRas [G12D,Q61H] (Homo sapiens (Human))	BDBM485666 (US10940139, Example 02769 \| US11000515, Compound T...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shy Therapeutics LLC US Patent					Assay Description Buffer-I: 50 mM Tris, pH 7.5 150 mM NaCl (optional) 1 mM MgCl2 1 mM DTT. KRas G12D mutant protein was expressed as...				US Patent US11000515 (2021) BindingDB Entry DOI: 10.7270/Q2V98C6R
Shy Therapeutics LLC US Patent					More data for this Ligand-Target Pair
GTPase KRas [G12D,Q61H] (Homo sapiens (Human))	BDBM485666 (US10940139, Example 02769 \| US11000515, Compound T...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following method was developed as specific assay for KRas G12D mutant protein.Buffer-I:50 mM Tris, pH 7.5150 mM NaCl (optional)1 mM MgCl21 mM DTT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FB56SS
TBA					More data for this Ligand-Target Pair
GTPase KRas [G12D,Q61H] (Homo sapiens (Human))	BDBM485666 (US10940139, Example 02769 \| US11000515, Compound T...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following method was developed as specific assay for KRas G12D mutant protein.Buffer-I: 50 mM Tris, pH 7.5 150 mM NaCl (optional) ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20G3PBB
TBA					More data for this Ligand-Target Pair