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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [1148-1435]' and Ligand = 'BDBM28284'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [1148-1435]


(Human immunodeficiency virus type 1)		BDBM28284
PNG
(1,3,4-oxadiazole substituted naphthyridine, 52 | N...)
Show SMILES CC(=O)Nc1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12
Show InChI InChI=1S/C25H18FN5O3/c1-14(32)28-18-10-6-16(7-11-18)21-19-3-2-12-27-22(19)24(33)23(29-21)25-31-30-20(34-25)13-15-4-8-17(26)9-5-15/h2-12,33H,13H2,1H3,(H,28,32)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
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AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



GSK



Assay Description
Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...

Bioorg Med Chem Lett 19: 1807-10 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.089
BindingDB Entry DOI: 10.7270/Q2TH8K1R
More data for this
Ligand-Target Pair