BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM50183624'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM50183624
PNG
(CHEMBL380522 | {(1S)-1-[N'-[(2S)-2-hydroxy-2-((1S,...)
Show SMILES COC(=O)N[C@H](C(=O)NN(Cc1ccc(cc1)C#Cc1cccnc1)C[C@@](O)(Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)C(C)(C)C
Show InChI InChI=1S/C41H45N5O6/c1-40(2,3)36(44-39(50)52-4)37(48)45-46(26-31-20-17-28(18-21-31)16-19-30-13-10-22-42-25-30)27-41(51,24-29-11-6-5-7-12-29)38(49)43-35-33-15-9-8-14-32(33)23-34(35)47/h5-15,17-18,20-22,25,34-36,47,51H,23-24,26-27H2,1-4H3,(H,43,49)(H,44,50)(H,45,48)/t34-,35+,36-,41+/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 7.80n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 protease

J Med Chem 49: 1828-32 (2006)


Article DOI: 10.1021/jm051239z
BindingDB Entry DOI: 10.7270/Q2PC3357
More data for this
Ligand-Target Pair