Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2' and Ligand = 'BDBM50180381'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50180381 (5-fluoro-2-(4-(7-(trifluoromethyl)imidazo[1,2-a]py...) Show SMILES Fc1ccc(-c2cc(ccn2)-c2cnc3nc(ccn23)C(F)(F)F)c(c1)C#N Show InChI InChI=1S/C19H9F4N5/c20-13-1-2-14(12(7-13)9-24)15-8-11(3-5-25-15)16-10-26-18-27-17(19(21,22)23)4-6-28(16)18/h1-8,10H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ
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