BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Gastrin/cholecystokinin type B receptor' and Ligand = 'BDBM50281711'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50281711 (1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its activity to inhibit the binding of [125I]-CCK-33 to Cholecystokinin type B receptor in guinea pig brain				Bioorg Med Chem Lett 3: 867-870 (1993) Article DOI: 10.1016/S0960-894X(00)80682-4 BindingDB Entry DOI: 10.7270/Q28S4PTK
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50281711 (1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glands				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50281711 (1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glands				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50281711 (1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its activity to inhibit the binding of [125I]-gastrin to gastric glands (gastrin) in guinea pig				Bioorg Med Chem Lett 3: 867-870 (1993) Article DOI: 10.1016/S0960-894X(00)80682-4 BindingDB Entry DOI: 10.7270/Q28S4PTK
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50281711 (1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptor				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair