BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gastrin/cholecystokinin type B receptor' and Ligand = 'BDBM50422152'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50422152 (CHEMBL432015) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin B receptor expressed in CHO-K1 cells by competitive radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00829 BindingDB Entry DOI: 10.7270/Q22J6GHJ
TBA					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50422152 (CHEMBL432015) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Binding affinity against human Cholecystokinin type B receptor in CHO-K1 cells using [125I]-Bolton-Hunter CCK-8 as radioligand				J Med Chem 39: 3030-4 (1996) Article DOI: 10.1021/jm960205b BindingDB Entry DOI: 10.7270/Q26H4JPR
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair