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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gastrin/cholecystokinin type B receptor' and Ligand = 'BDBM50472873'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gastrin/cholecystokinin type B receptor


(Homo sapiens (Human))		BDBM50472873
PNG
(CHEMBL120363)
Show SMILES [H][C@]12C[C@]3([H])C[C@]([H])(C1)CC(CN1c4ccccc4N(c4ccccc4)C(=O)C(NC(=O)Nc4cccc(c4)C(O)=O)C1=O)(C2)C3 |TLB:5:3:44:6.9.8,THB:2:3:9:1.44.8,2:1:9:3.45.5,5:6:44:3.45.2|
Show InChI InChI=1S/C34H34N4O5/c39-30-29(36-33(43)35-25-8-6-7-24(16-25)32(41)42)31(40)38(26-9-2-1-3-10-26)28-12-5-4-11-27(28)37(30)20-34-17-21-13-22(18-34)15-23(14-21)19-34/h1-12,16,21-23,29H,13-15,17-20H2,(H,41,42)(H2,35,36,43)/t21-,22+,23-,29?,34?
PDB

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PC cid
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Article
PubMed
 0.977n/an/an/an/an/an/an/an/a



Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL


Assay Description
In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranes

J Med Chem 43: 3596-613 (2000)


Article DOI: 10.1021/jm990967h
BindingDB Entry DOI: 10.7270/Q26H4M5V
More data for this
Ligand-Target Pair