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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gastrin/cholecystokinin type B receptor' and Ligand = 'BDBM50472874'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gastrin/cholecystokinin type B receptor


(Homo sapiens (Human))		BDBM50472874
PNG
(CHEMBL118189)
Show SMILES [H][C@]12C[C@]3([H])C[C@]([H])(C1)CC(CN1c4ccccc4N(c4ccccc4)C(=O)C(NC(=O)Nc4ccc(Br)cc4)C1=O)(C2)C3 |TLB:8:1:43:6.9.5,8:6:43:1.42.2,THB:2:3:9:1.42.8,2:1:9:3.43.5|
Show InChI InChI=1S/C33H33BrN4O3/c34-24-10-12-25(13-11-24)35-32(41)36-29-30(39)37(20-33-17-21-14-22(18-33)16-23(15-21)19-33)27-8-4-5-9-28(27)38(31(29)40)26-6-2-1-3-7-26/h1-13,21-23,29H,14-20H2,(H2,35,36,41)/t21-,22+,23-,29?,33?
PDB

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Article
PubMed
 1.40n/an/an/an/an/an/an/an/a



Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL


Assay Description
In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranes

J Med Chem 43: 3596-613 (2000)


Article DOI: 10.1021/jm990967h
BindingDB Entry DOI: 10.7270/Q26H4M5V
More data for this
Ligand-Target Pair