Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human)) | BDBM50549226 (CHEMBL4795913) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I][3-iodo Tyr12,Leu15]gastrin-I from human CCK2R expressed in human A431 cells measured after 1 hr by gamma counter analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01233 BindingDB Entry DOI: 10.7270/Q2P84GJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin/cholecystokinin type B receptor (RAT) | BDBM50549226 (CHEMBL4795913) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at rat CCK2R expressed in rat AR42J cells assessed as intracellular calcium mobilization measured after 24 hrs by Fluo-4AM dye based... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01233 BindingDB Entry DOI: 10.7270/Q2P84GJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human)) | BDBM50549226 (CHEMBL4795913) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human CCK2R expressed in human A431 cells assessed as intracellular calcium mobilization measured after 24 hrs by Fluo-4AM dye ba... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01233 BindingDB Entry DOI: 10.7270/Q2P84GJ2 | |||||||||||
More data for this Ligand-Target Pair |