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Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM263105'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Murine norovirus 1)		BDBM263105
PNG
(US9708359, 30)
Show SMILES COc1nc(C)nc2n(cc(C#N)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H16N4O5/c1-6-16-12-9(13(17-6)22-2)7(3-15)4-18(12)14-11(21)10(20)8(5-19)23-14/h4,8,10-11,14,19-21H,5H2,1-2H3/t8-,10-,11-,14-/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+5n/an/an/an/a



Chimerix, Inc.; The Regents of the University of Michigan

US Patent


Assay Description
Polymerase reactions (10 μL) were conducted for 60 minutes at 37° C. Nucleoside triphosphates (NTPs) were present at 100 μM each, with 0.05...

US Patent US9708359 (2017)


BindingDB Entry DOI: 10.7270/Q22F7QGB
More data for this
Ligand-Target Pair