Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM345821'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)	BDBM345821 (US10202367, Compound 2) Show SMILES CCCN(CC)CCNC(=O)C1CCN(CC2N=C(OC2C)c2ccccc2C)CC1 |c:17| Show InChI InChI=1S/C25H40N4O2/c1-5-14-28(6-2)17-13-26-24(30)21-11-15-29(16-12-21)18-23-20(4)31-25(27-23)22-10-8-7-9-19(22)3/h7-10,20-21,23H,5-6,11-18H2,1-4H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas US Patent					Assay Description This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...				US Patent US10202367 (2019) BindingDB Entry DOI: 10.7270/Q23B6277
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