Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM345859'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)	BDBM345859 (US10202367, Compound 5) Show SMILES CC(C)C1CCN(CCCNC(=O)C2CCN(CC3N=C(OC3C)c3ccccc3C)CC2)CC1 |c:19| Show InChI InChI=1S/C29H46N4O2/c1-21(2)24-10-16-32(17-11-24)15-7-14-30-28(34)25-12-18-33(19-13-25)20-27-23(4)35-29(31-27)26-9-6-5-8-22(26)3/h5-6,8-9,21,23-25,27H,7,10-20H2,1-4H3,(H,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas US Patent					Assay Description This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...				US Patent US10202367 (2019) BindingDB Entry DOI: 10.7270/Q23B6277
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