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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM345899'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)		BDBM345899
PNG
(US10202367, Compound 45)
Show SMILES COc1cccc(C)c1C1=NC(CN2CCC(CC2)C(=O)NCCCN2C[C@@H](C)C[C@@H](C)C2)C(C)O1 |r,t:10|
Show InChI InChI=1S/C29H46N4O3/c1-20-16-21(2)18-33(17-20)13-7-12-30-28(34)24-10-14-32(15-11-24)19-25-23(4)36-29(31-25)27-22(3)8-6-9-26(27)35-5/h6,8-9,20-21,23-25H,7,10-19H2,1-5H3,(H,30,34)/t20-,21+,23?,25?
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 423n/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas

US Patent


Assay Description
This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...

US Patent US10202367 (2019)


BindingDB Entry DOI: 10.7270/Q23B6277
More data for this
Ligand-Target Pair