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Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-1206,R1052K]/[1678-1691]' and Ligand = 'BDBM3902'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [1027-1206,R1052K]/[1678-1691]


(Hepatitis C virus)		BDBM3902
PNG
((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](C[C@H]1C(=O)NN(CC)C(=O)N[C@@H](C)c1ccccc1)OCc1ccccc1 |r|
Show InChI InChI=1S/C45H64N8O12/c1-8-27(5)39(50-40(59)33(20-21-36(55)56)48-41(60)34(23-37(57)58)47-29(7)54)43(62)49-38(26(3)4)44(63)52-24-32(65-25-30-16-12-10-13-17-30)22-35(52)42(61)51-53(9-2)45(64)46-28(6)31-18-14-11-15-19-31/h10-19,26-28,32-35,38-39H,8-9,20-25H2,1-7H3,(H,46,64)(H,47,54)(H,48,60)(H,49,62)(H,50,59)(H,51,61)(H,55,56)(H,57,58)/t27-,28-,32+,33+,34-,35-,38-,39-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 85n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd.



Assay Description
The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...

J Med Chem 47: 3788-99 (2004)


Article DOI: 10.1021/jm049864b
BindingDB Entry DOI: 10.7270/Q2125QTZ
More data for this
Ligand-Target Pair