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Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-1207,A156S]' and Ligand = 'BDBM241941'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [1027-1207,A156S]


(Hepatitis C virus genotype 1b (isolate Con1) (HCV))		BDBM241941
PNG
(US9422333, I-6)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#8]C([#6])([#6])[#6])-[#6](=O)-[#7]-1-[#6]-[#6]2-[#6@@H](-[#6@H]-1-[#6](=O)-[#7]-[#6](-[#6]-[#6]-1-[#6]-[#6]-[#6]-1)-[#6](=O)-[#6](-[#7])=O)C2([#6])[#6] |r,w:27.28|
Show InChI InChI=1S/C30H46N4O7/c1-16(2)13-18(35)11-12-20(33-28(40)41-29(3,4)5)27(39)34-15-19-22(30(19,6)7)23(34)26(38)32-21(24(36)25(31)37)14-17-9-8-10-17/h13,17,19-23H,8-12,14-15H2,1-7H3,(H2,31,37)(H,32,38)(H,33,40)/t19?,20-,21?,22-,23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>3.00E+3n/an/an/an/a7.5n/a



Celgene Avilomics Research, Inc.

US Patent


Assay Description
The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...

US Patent US9422333 (2016)


BindingDB Entry DOI: 10.7270/Q2B27T6P
More data for this
Ligand-Target Pair