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Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1658-1692]' and Ligand = 'BDBM92628'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [1658-1692]


(Hepatitis C virus)		BDBM92628
PNG
((1R)-1-(2,4-difluoro-3-phenoxyphenyl)propan-1-amin...)
Show SMILES CC[C@@H](N)c1ccc(Cl)c(Oc2ccccc2)c1F |r|
Show InChI InChI=1S/C15H15ClFNO/c1-2-13(18)11-8-9-12(16)15(14(11)17)19-10-6-4-3-5-7-10/h3-9,13H,2,18H2,1H3/t13-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/a25



Astex Pharmaceuticals



Assay Description
The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...

Nat Chem Biol 8: 920-5 (2012)


Article DOI: 10.1038/nchembio.1081
BindingDB Entry DOI: 10.7270/Q26Q1VVN
More data for this
Ligand-Target Pair