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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1973-2419,L2003V]' and Ligand = 'BDBM243436'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [1973-2419,L2003V]


(Hepatitis C virus genotype 1b (isolate Con1) (HCV))		BDBM243436
PNG
(US9427428, 17 | US9427428, 21)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC |r|
Show InChI InChI=1S/C43H50N8O7/c1-7-24(2)36(48-42(54)57-5)40(52)50-18-8-10-34(50)38-44-23-33(47-38)30-15-14-26-20-27(12-13-28(26)21-30)29-16-17-31-32(22-29)46-39(45-31)35-11-9-19-51(35)41(53)37(25(3)56-4)49-43(55)58-6/h12-17,20-25,34-37H,7-11,18-19H2,1-6H3,(H,48,54)(H,49,55)/b29-27-,33-30+/t24-,25+,34-,35-,36-,37-/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0370n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair