Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1973-2419,Y2165C]' and Ligand = 'BDBM245918'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1973-2419,Y2165C] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM245918 (US9433609, 2 | US9433609, 4) Show SMILES CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc2ccc(cc2[nH]1)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C38H46N8O7/c1-21(2)31(43-37(49)52-5)35(47)45-17-7-9-29(45)33-39-20-28(42-33)24-13-11-23(12-14-24)25-15-16-26-27(19-25)41-34(40-26)30-10-8-18-46(30)36(48)32(22(3)51-4)44-38(50)53-6/h11-16,19-22,29-32H,7-10,17-18H2,1-6H3,(H,43,49)(H,44,50)/b25-23-,28-24-/t22-,29+,30+,31+,32+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0130	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...				US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2419,Y2165C] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM245918 (US9433609, 2 | US9433609, 4) Show SMILES CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc2ccc(cc2[nH]1)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C38H46N8O7/c1-21(2)31(43-37(49)52-5)35(47)45-17-7-9-29(45)33-39-20-28(42-33)24-13-11-23(12-14-24)25-15-16-26-27(19-25)41-34(40-26)30-10-8-18-46(30)36(48)32(22(3)51-4)44-38(50)53-6/h11-16,19-22,29-32H,7-10,17-18H2,1-6H3,(H,43,49)(H,44,50)/b25-23-,28-24-/t22-,29+,30+,31+,32+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.655	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...				US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD
					More data for this Ligand-Target Pair