Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1973-2419,Y2165H]' and Ligand = 'BDBM243448'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1973-2419,Y2165H] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM243448 (US9427428, 12 | US9433609, 12) Show SMILES COC(=O)NC(C1CCOCC1)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)C(NC(=O)OC)C1CCOCC1 |r| Show InChI InChI=1S/C46H52N8O8/c1-59-45(57)51-39(27-13-19-61-20-14-27)43(55)53-17-3-5-37(53)41-47-26-36(50-41)33-10-9-29-23-30(7-8-31(29)24-33)32-11-12-34-35(25-32)49-42(48-34)38-6-4-18-54(38)44(56)40(52-46(58)60-2)28-15-21-62-22-16-28/h7-12,23-28,37-40H,3-6,13-22H2,1-2H3,(H,51,57)(H,52,58)/b32-30+,36-33-/t37-,38-,39?,40?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.275	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...				US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2419,Y2165H] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM243448 (US9427428, 12 | US9433609, 12) Show SMILES COC(=O)NC(C1CCOCC1)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)C(NC(=O)OC)C1CCOCC1 |r| Show InChI InChI=1S/C46H52N8O8/c1-59-45(57)51-39(27-13-19-61-20-14-27)43(55)53-17-3-5-37(53)41-47-26-36(50-41)33-10-9-29-23-30(7-8-31(29)24-33)32-11-12-34-35(25-32)49-42(48-34)38-6-4-18-54(38)44(56)40(52-46(58)60-2)28-15-21-62-22-16-28/h7-12,23-28,37-40H,3-6,13-22H2,1-2H3,(H,51,57)(H,52,58)/b32-30+,36-33-/t37-,38-,39?,40?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.275	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...				US Patent US9427428 (2016) BindingDB Entry DOI: 10.7270/Q2JD4VPJ
					More data for this Ligand-Target Pair