Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-3010]' and Ligand = 'BDBM240870'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM240870 (US9394331, 132) Show SMILES COc1nc(N)nc2n(cnc12)C1OC2COP(=O)(OCC(C)(C)C)O[C@H]2[C@]11CCO1 |r| Show InChI InChI=1S/C18H26N5O7P/c1-17(2,3)8-28-31(24)27-7-10-12(30-31)18(5-6-26-18)15(29-10)23-9-20-11-13(23)21-16(19)22-14(11)25-4/h9-10,12,15H,5-8H2,1-4H3,(H2,19,21,22)/t10?,12-,15?,18-,31?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	7.5	27
Gilead Pharmasset LLC US Patent					Assay Description The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...				US Patent US9394331 (2016) BindingDB Entry DOI: 10.7270/Q2W094TH
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