Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein [810-3010]' and Ligand = 'BDBM243438'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [810-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM243438 (US9427428, 11) Show SMILES CO[C@H](C)[C@@H](NC(=O)OC)C(=O)N1CCC[C@@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C42H48N8O7/c1-23(2)35(47-41(53)56-5)39(51)50-18-8-10-34(50)38-44-30-16-15-28(21-31(30)45-38)26-11-12-27-20-29(14-13-25(27)19-26)32-22-43-37(46-32)33-9-7-17-49(33)40(52)36(24(3)55-4)48-42(54)57-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,47,53)(H,48,54)/b28-26-,32-29+/t24-,33-,34+,35-,36-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0120	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...				US Patent US9427428 (2016) BindingDB Entry DOI: 10.7270/Q2JD4VPJ
					More data for this Ligand-Target Pair
Genome polyprotein [810-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM243438 (US9427428, 11) Show SMILES CO[C@H](C)[C@@H](NC(=O)OC)C(=O)N1CCC[C@@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C42H48N8O7/c1-23(2)35(47-41(53)56-5)39(51)50-18-8-10-34(50)38-44-30-16-15-28(21-31(30)45-38)26-11-12-27-20-29(14-13-25(27)19-26)32-22-43-37(46-32)33-9-7-17-49(33)40(52)36(24(3)55-4)48-42(54)57-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,47,53)(H,48,54)/b28-26-,32-29+/t24-,33-,34+,35-,36-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00600	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...				US Patent US9427428 (2016) BindingDB Entry DOI: 10.7270/Q2JD4VPJ
					More data for this Ligand-Target Pair