BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50168095'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50168095 (CHEMBL3799656) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Antagonist activity at wild type human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation incu...				Bioorg Med Chem 24: 2852-63 (2016) Article DOI: 10.1016/j.bmc.2016.04.053 BindingDB Entry DOI: 10.7270/Q27P919J
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50168095 (CHEMBL3799656) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHO-K1 cells after 3 hrs by scintillation counting method				Bioorg Med Chem 24: 2852-63 (2016) Article DOI: 10.1016/j.bmc.2016.04.053 BindingDB Entry DOI: 10.7270/Q27P919J
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair