BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50277057'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM50277057
PNG
(CHEMBL4174154)
Show SMILES CCCCCCN1C(=O)CC(SC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)C1=O |r|
Show InChI InChI=1S/C163H241N45O49S2/c1-13-14-15-26-56-208-125(222)70-119(161(208)257)259-77-118(157(253)185-99(37-28-55-177-163(173)174)138(234)183-98(36-27-54-176-162(171)172)137(233)181-82(8)134(230)182-101(47-50-121(167)218)140(236)196-112(67-126(223)224)148(244)193-108(60-86-29-18-16-19-30-86)151(247)205-129(81(6)7)158(254)188-102(48-51-122(168)219)141(237)194-110(64-90-71-178-96-34-23-22-33-94(90)96)147(243)190-104(58-79(2)3)143(239)187-103(52-57-258-12)142(238)195-111(66-123(169)220)153(249)206-130(83(9)212)133(170)229)203-150(246)114(69-128(227)228)197-144(240)105(59-80(4)5)189-145(241)106(62-88-38-42-92(215)43-39-88)191-139(235)97(35-24-25-53-164)184-155(251)116(75-210)201-146(242)107(63-89-40-44-93(216)45-41-89)192-149(245)113(68-127(225)226)198-156(252)117(76-211)202-160(256)132(85(11)214)207-152(248)109(61-87-31-20-17-21-32-87)199-159(255)131(84(10)213)204-124(221)73-179-136(232)100(46-49-120(166)217)186-154(250)115(74-209)200-135(231)95(165)65-91-72-175-78-180-91/h16-23,29-34,38-45,71-72,78-85,95,97-119,129-132,178,209-216H,13-15,24-28,35-37,46-70,73-77,164-165H2,1-12H3,(H2,166,217)(H2,167,218)(H2,168,219)(H2,169,220)(H2,170,229)(H,175,180)(H,179,232)(H,181,233)(H,182,230)(H,183,234)(H,184,251)(H,185,253)(H,186,250)(H,187,239)(H,188,254)(H,189,241)(H,190,243)(H,191,235)(H,192,245)(H,193,244)(H,194,237)(H,195,238)(H,196,236)(H,197,240)(H,198,252)(H,199,255)(H,200,231)(H,201,242)(H,202,256)(H,203,246)(H,204,221)(H,205,247)(H,206,249)(H,207,248)(H,223,224)(H,225,226)(H,227,228)(H4,171,172,176)(H4,173,174,177)/t82-,83+,84+,85+,95-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119?,129-,130-,131-,132-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 0.860n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human GCGR expressed in HEK293 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assay

Eur J Med Chem 138: 1158-1169 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.046
BindingDB Entry DOI: 10.7270/Q2QC061V
More data for this
Ligand-Target Pair