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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50277078'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM50277078
PNG
(CHEMBL4170727)
Show SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
Show InChI InChI=1S/C151H222N44O48S2/c1-71(2)50-95(132(226)176-94(45-49-245-9)131(225)183-102(58-114(157)208)142(236)194-119(74(6)200)122(158)216)178-137(231)101(56-81-62-166-87-27-17-16-26-85(81)87)182-130(224)93(41-44-113(156)207)175-147(241)110(69-244)192-136(230)97(52-77-22-12-10-13-23-77)180-138(232)103(59-116(210)211)184-129(223)92(40-43-112(155)206)170-123(217)73(5)169-126(220)89(29-20-47-164-150(159)160)171-127(221)90(30-21-48-165-151(161)162)173-145(239)108(67-198)190-140(234)105(61-118(214)215)185-133(227)96(51-72(3)4)177-134(228)98(54-79-31-35-83(203)36-32-79)179-128(222)88(28-18-19-46-152)172-144(238)107(66-197)189-135(229)99(55-80-33-37-84(204)38-34-80)181-139(233)104(60-117(212)213)186-146(240)109(68-199)191-149(243)121(76(8)202)195-141(235)100(53-78-24-14-11-15-25-78)187-148(242)120(75(7)201)193-115(209)64-167-125(219)91(39-42-111(154)205)174-143(237)106(65-196)188-124(218)86(153)57-82-63-163-70-168-82/h10-17,22-27,31-38,62-63,70-76,86,88-110,119-121,166,196-204,244H,18-21,28-30,39-61,64-69,152-153H2,1-9H3,(H2,154,205)(H2,155,206)(H2,156,207)(H2,157,208)(H2,158,216)(H,163,168)(H,167,219)(H,169,220)(H,170,217)(H,171,221)(H,172,238)(H,173,239)(H,174,237)(H,175,241)(H,176,226)(H,177,228)(H,178,231)(H,179,222)(H,180,232)(H,181,233)(H,182,224)(H,183,225)(H,184,223)(H,185,227)(H,186,240)(H,187,242)(H,188,218)(H,189,229)(H,190,234)(H,191,243)(H,192,230)(H,193,209)(H,194,236)(H,195,235)(H,210,211)(H,212,213)(H,214,215)(H4,159,160,164)(H4,161,162,165)/t73-,74+,75+,76+,86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-,120-,121-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 0.75n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human GCGR expressed in HEK293 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assay

Eur J Med Chem 138: 1158-1169 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.046
BindingDB Entry DOI: 10.7270/Q2QC061V
More data for this
Ligand-Target Pair