BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50525881'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM50525881
PNG
(CHEMBL4513792)
Show SMILES CC(C)C[C@@H](c1ccc(cc1)C(=O)NCCC(O)=O)n1ncc2cc(c(C)cc12)-c1ccc(cc1C)C(F)(F)F |r|
Show InChI InChI=1S/C31H32F3N3O3/c1-18(2)13-27(21-5-7-22(8-6-21)30(40)35-12-11-29(38)39)37-28-15-20(4)26(16-23(28)17-36-37)25-10-9-24(14-19(25)3)31(32,33)34/h5-10,14-18,27H,11-13H2,1-4H3,(H,35,40)(H,38,39)/t27-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Janssen Research & Development, L.L.C.

Curated by ChEMBL


Assay Description
Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay

Bioorg Med Chem Lett 29: (2019)


Article DOI: 10.1016/j.bmcl.2019.126668
BindingDB Entry DOI: 10.7270/Q2902776
More data for this
Ligand-Target Pair