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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50525884'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM50525884
PNG
(CHEMBL4589676)
Show SMILES CC(C)C[C@@H](c1ccc(cc1)C(=O)NCCC(O)=O)n1cc2cc(c(C)cc2n1)-c1ccc(cc1C)C(F)(F)F |r|
Show InChI InChI=1S/C31H32F3N3O3/c1-18(2)13-28(21-5-7-22(8-6-21)30(40)35-12-11-29(38)39)37-17-23-16-26(20(4)15-27(23)36-37)25-10-9-24(14-19(25)3)31(32,33)34/h5-10,14-18,28H,11-13H2,1-4H3,(H,35,40)(H,38,39)/t28-/m0/s1
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PC cid
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Article
PubMed
 25n/an/an/an/an/an/an/an/a



Janssen Research & Development, L.L.C.

Curated by ChEMBL


Assay Description
Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay

Bioorg Med Chem Lett 29: (2019)


Article DOI: 10.1016/j.bmcl.2019.126668
BindingDB Entry DOI: 10.7270/Q2902776
More data for this
Ligand-Target Pair