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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 2 receptor' and Ligand = 'BDBM50183660'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon-like peptide 2 receptor


(Homo sapiens (Human))		BDBM50183660
PNG
(CHEMBL3824079)
Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r|
Show InChI InChI=1S/C173H259N43O52S/c1-21-26-50-104(192-149(245)108(55-57-129(226)227)193-158(254)120(73-132(232)233)206-165(261)124(81-218)209-155(251)114(65-96-44-32-28-33-45-96)201-164(260)123(80-217)190-128(225)79-185-146(242)119(72-131(230)231)189-127(224)78-184-145(241)102(175)68-99-77-181-82-186-99)147(243)203-117(69-100-48-41-60-269-100)163(259)215-141(94(20)221)172(268)213-137(88(14)24-4)168(264)207-111(62-84(8)9)153(249)205-122(75-134(236)237)160(256)199-113(64-95-42-30-27-31-43-95)154(250)197-110(61-83(6)7)152(248)188-90(16)143(239)187-91(17)144(240)191-106(53-40-59-182-173(179)180)148(244)204-121(74-133(234)235)159(255)200-115(66-97-46-34-29-35-47-97)162(258)212-136(87(13)23-3)167(263)208-118(70-126(177)223)157(253)202-116(67-98-76-183-103-51-37-36-49-101(98)103)156(252)198-112(63-85(10)11)161(257)211-135(86(12)22-2)166(262)195-107(54-56-125(176)222)151(247)214-139(92(18)219)170(266)194-105(52-38-39-58-174)150(246)210-138(89(15)25-5)169(265)216-140(93(19)220)171(267)196-109(142(178)238)71-130(228)229/h27-37,41-49,51,60,76-77,82-94,102,104-124,135-141,183,217-221H,21-26,38-40,50,52-59,61-75,78-81,174-175H2,1-20H3,(H2,176,222)(H2,177,223)(H2,178,238)(H,181,186)(H,184,241)(H,185,242)(H,187,239)(H,188,248)(H,189,224)(H,190,225)(H,191,240)(H,192,245)(H,193,254)(H,194,266)(H,195,262)(H,196,267)(H,197,250)(H,198,252)(H,199,256)(H,200,255)(H,201,260)(H,202,253)(H,203,243)(H,204,244)(H,205,249)(H,206,261)(H,207,264)(H,208,263)(H,209,251)(H,210,246)(H,211,257)(H,212,258)(H,213,268)(H,214,247)(H,215,259)(H,216,265)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H4,179,180,182)/t86-,87-,88-,89-,90-,91-,92+,93+,94+,102-,104?,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117+,118-,119-,120-,121-,122-,123-,124-,135-,136-,137-,138-,139-,140-,141-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 0.0700n/an/an/an/a



Ferring Research Institute Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay

J Med Chem 59: 3129-39 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7
More data for this
Ligand-Target Pair