Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM445027'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM445027 (US10668167, Compound 35) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(NCc2ccc(N)cc2)nc1 |r,c:14,t:10| Show InChI InChI=1S/C34H38FN3O6/c1-31-12-11-23(40)13-21(31)6-9-24-25-14-28-34(27(42)18-39,32(25,2)15-26(41)33(24,31)35)44-30(43-28)20-5-10-29(38-17-20)37-16-19-3-7-22(36)8-4-19/h3-5,7-8,10-13,17,24-26,28,30,39,41H,6,9,14-16,18,36H2,1-2H3,(H,37,38)/t24-,25-,26-,28+,30+,31-,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM445027 (US10668167, Compound 35) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(NCc2ccc(N)cc2)nc1 |r,c:14,t:10| Show InChI InChI=1S/C34H38FN3O6/c1-31-12-11-23(40)13-21(31)6-9-24-25-14-28-34(27(42)18-39,32(25,2)15-26(41)33(24,31)35)44-30(43-28)20-5-10-29(38-17-20)37-16-19-3-7-22(36)8-4-19/h3-5,7-8,10-13,17,24-26,28,30,39,41H,6,9,14-16,18,36H2,1-2H3,(H,37,38)/t24-,25-,26-,28+,30+,31-,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair