Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM445042'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM445042 (US10668167, Compound 53) Show SMILES C[C@@H](c1ccc(cc1)[C@H]1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO)c1cccc(N)c1 |r,c:22,t:18| Show InChI InChI=1S/C36H39F2NO6/c1-19(22-5-4-6-23(39)13-22)20-7-9-21(10-8-20)32-44-31-16-25-26-15-28(37)27-14-24(41)11-12-33(27,2)35(26,38)29(42)17-34(25,3)36(31,45-32)30(43)18-40/h4-14,19,25-26,28-29,31-32,40,42H,15-18,39H2,1-3H3/t19-,25-,26-,28-,29-,31+,32-,33-,34-,35-,36+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
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