Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50249144'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249144 (15-(2-hydroxyethyl)-N-(1,3-thiazol-2-yl)tetracyclo...) Show SMILES OCCC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1nccs1 |TLB:2:3:6.11:13.18,10:11:4.3:13.18,14:13:6.11:4.3,THB:19:3:6.11:13.18,(.97,-31.91,;2.31,-32.69,;3.64,-31.91,;4.99,-32.69,;5.49,-33.46,;5.5,-35.65,;3.63,-36.17,;2.29,-36.94,;.95,-36.17,;.96,-34.62,;2.28,-33.85,;3.6,-34.77,;4.99,-34.1,;6.52,-35,;7.79,-34.26,;9.07,-34.99,;9.07,-36.48,;7.79,-37.22,;6.52,-36.48,;5.74,-31.35,;4.95,-30.02,;7.28,-31.33,;8.04,-29.99,;9.58,-29.81,;9.88,-28.29,;8.54,-27.54,;7.4,-28.58,)| Show InChI InChI=1S/C22H20N2O2S/c25-11-9-22(20(26)24-21-23-10-12-27-21)13-18-14-5-1-3-7-16(14)19(22)17-8-4-2-6-15(17)18/h1-8,10,12,18-19,25H,9,11,13H2,(H,23,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	303	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assay				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249144 (15-(2-hydroxyethyl)-N-(1,3-thiazol-2-yl)tetracyclo...) Show SMILES OCCC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1nccs1 |TLB:2:3:6.11:13.18,10:11:4.3:13.18,14:13:6.11:4.3,THB:19:3:6.11:13.18,(.97,-31.91,;2.31,-32.69,;3.64,-31.91,;4.99,-32.69,;5.49,-33.46,;5.5,-35.65,;3.63,-36.17,;2.29,-36.94,;.95,-36.17,;.96,-34.62,;2.28,-33.85,;3.6,-34.77,;4.99,-34.1,;6.52,-35,;7.79,-34.26,;9.07,-34.99,;9.07,-36.48,;7.79,-37.22,;6.52,-36.48,;5.74,-31.35,;4.95,-30.02,;7.28,-31.33,;8.04,-29.99,;9.58,-29.81,;9.88,-28.29,;8.54,-27.54,;7.4,-28.58,)| Show InChI InChI=1S/C22H20N2O2S/c25-11-9-22(20(26)24-21-23-10-12-27-21)13-18-14-5-1-3-7-16(14)19(22)17-8-4-2-6-15(17)18/h1-8,10,12,18-19,25H,9,11,13H2,(H,23,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair