Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50355724'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355724 (CHEMBL1911159) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(cc1)C(O)=O)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C25H20N4O4S/c1-25(2,23(32)28-24-29-26-13-34-24)20-16-5-3-4-6-19(16)33-21-17(20)11-12-18(27-21)14-7-9-15(10-8-14)22(30)31/h3-13,20H,1-2H3,(H,30,31)(H,28,29,32)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of GS-red from glucocorticoid receptor by fluorescence polarization assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355724 (CHEMBL1911159) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(cc1)C(O)=O)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C25H20N4O4S/c1-25(2,23(32)28-24-29-26-13-34-24)20-16-5-3-4-6-19(16)33-21-17(20)11-12-18(27-21)14-7-9-15(10-8-14)22(30)31/h3-13,20H,1-2H3,(H,30,31)(H,28,29,32)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor alpha in IL-1beta-stimulated human A549 cells assessed as inhibition of NFkappaB-dependent E-sele...				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355724 (CHEMBL1911159) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(cc1)C(O)=O)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C25H20N4O4S/c1-25(2,23(32)28-24-29-26-13-34-24)20-16-5-3-4-6-19(16)33-21-17(20)11-12-18(27-21)14-7-9-15(10-8-14)22(30)31/h3-13,20H,1-2H3,(H,30,31)(H,28,29,32)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	544	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 resp...				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355724 (CHEMBL1911159) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(cc1)C(O)=O)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C25H20N4O4S/c1-25(2,23(32)28-24-29-26-13-34-24)20-16-5-3-4-6-19(16)33-21-17(20)11-12-18(27-21)14-7-9-15(10-8-14)22(30)31/h3-13,20H,1-2H3,(H,30,31)(H,28,29,32)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355724 (CHEMBL1911159) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(cc1)C(O)=O)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C25H20N4O4S/c1-25(2,23(32)28-24-29-26-13-34-24)20-16-5-3-4-6-19(16)33-21-17(20)11-12-18(27-21)14-7-9-15(10-8-14)22(30)31/h3-13,20H,1-2H3,(H,30,31)(H,28,29,32)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at GR-alpha in human NP1 Hela cells assessed as inhibition of GAL4-DBD after 20 hrs by luciferase reporter gene assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair