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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50415807'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50415807
PNG
(CHEMBL1090973)
Show SMILES CCCn1nc(C)c2c(Cl)c(cnc12)C(=O)NCc1ccc(cc1)-c1c(C)noc1C
Show InChI InChI=1S/C23H24ClN5O2/c1-5-10-29-22-20(13(2)27-29)21(24)18(12-25-22)23(30)26-11-16-6-8-17(9-7-16)19-14(3)28-31-15(19)4/h6-9,12H,5,10-11H2,1-4H3,(H,26,30)
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Similars
Article
PubMed
n/an/a 251n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...

Bioorg Med Chem Lett 20: 2340-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.133
BindingDB Entry DOI: 10.7270/Q2SF2XDJ
More data for this
Ligand-Target Pair