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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucose-dependent insulinotropic receptor' and Ligand = 'BDBM50268608'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268608
PNG
(CHEMBL4072360)
Show SMILES CN(c1ccc(cc1F)S(C)(=O)=O)c1ncnc2c(coc12)C1CCN(CC1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C24H29FN4O5S/c1-24(2,3)34-23(30)29-10-8-15(9-11-29)17-13-33-21-20(17)26-14-27-22(21)28(4)19-7-6-16(12-18(19)25)35(5,31)32/h6-7,12-15H,8-11H2,1-5H3
PDB

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PC cid
PC sid
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Similars
Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair