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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucose-dependent insulinotropic receptor' and Ligand = 'BDBM50268614'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268614
PNG
(CHEMBL4098382)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1coc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12
Show InChI InChI=1S/C23H27FN4O5S/c1-23(2,3)33-22(29)28-9-7-14(8-10-28)16-12-32-20-19(16)25-13-26-21(20)27-18-6-5-15(11-17(18)24)34(4,30)31/h5-6,11-14H,7-10H2,1-4H3,(H,25,26,27)
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Article
PubMed
n/an/an/an/a 129n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair