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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucose-dependent insulinotropic receptor' and Ligand = 'BDBM50268630'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268630
PNG
(CHEMBL4086445)
Show SMILES CC(O)c1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C26H28N6O4S/c1-16(33)19-12-27-26(28-13-19)31-8-5-17(6-9-31)21-14-36-24-23(21)29-15-30-25(24)32-10-7-18-11-20(37(2,34)35)3-4-22(18)32/h3-4,11-17,33H,5-10H2,1-2H3
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Article
PubMed
n/an/an/an/a 586n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair