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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate carboxypeptidase 2' and Ligand = 'BDBM479422'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM479422
PNG
(US10894807, ID P215)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](Cc1ccc(NC(=O)c2ccc(cc2)-n2cc(CCCF)nn2)cc1)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C27H29FN6O8/c28-13-1-2-19-15-34(33-32-19)20-9-5-17(6-10-20)24(37)29-18-7-3-16(4-8-18)14-22(26(40)41)31-27(42)30-21(25(38)39)11-12-23(35)36/h3-10,15,21-22H,1-2,11-14H2,(H,29,37)(H,35,36)(H,38,39)(H,40,41)(H2,30,31,42)/t21-,22-/m0/s1
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KEGG

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PC cid
PC sid
UniChem
US Patent
 2.20n/an/an/an/an/an/an/an/a



Siemens Medical Solutions USA, Inc.

US Patent


Assay Description
The inhibitory activity of all compounds was determined using a fluorescent assay of human PSMA activity. The enzyme used in the assay was purchased ...

US Patent US10894807 (2021)


BindingDB Entry DOI: 10.7270/Q2SN0D25
More data for this
Ligand-Target Pair