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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50324405'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50324405
PNG
((E)-4-(2-(3-Nitrostyryl)-4-oxobenzo[g]quinazolin-3...)
Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2cc3ccccc3cc2c1=O
Show InChI InChI=1S/C27H17N3O5/c31-26-23-15-19-5-1-2-6-20(19)16-24(23)28-25(13-8-17-4-3-7-22(14-17)30(34)35)29(26)21-11-9-18(10-12-21)27(32)33/h1-16H,(H,32,33)/b13-8+
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PC sid
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Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...

J Med Chem 53: 5476-90 (2010)


Article DOI: 10.1021/jm100027p
BindingDB Entry DOI: 10.7270/Q2DR2VQF
More data for this
Ligand-Target Pair