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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2C' and Ligand = 'BDBM50324394'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))		BDBM50324394
PNG
((E)-4-(8-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...)
Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2c(Cl)cccc2c1=O
Show InChI InChI=1S/C23H14ClN3O5/c24-19-6-2-5-18-21(19)25-20(12-7-14-3-1-4-17(13-14)27(31)32)26(22(18)28)16-10-8-15(9-11-16)23(29)30/h1-13H,(H,29,30)/b12-7+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...

J Med Chem 53: 5476-90 (2010)


Article DOI: 10.1021/jm100027p
BindingDB Entry DOI: 10.7270/Q2DR2VQF
More data for this
Ligand-Target Pair