Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50001260![]() (3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes. | J Med Chem 35: 3423-5 (1992) BindingDB Entry DOI: 10.7270/Q2RR1X68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50001260![]() (3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes. | J Med Chem 35: 3423-5 (1992) BindingDB Entry DOI: 10.7270/Q2RR1X68 | |||||||||||
More data for this Ligand-Target Pair |